A Case of Granulomatosis with Polyangiitis with Submandibular Abscess as Primary Manifestation

Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a rare immunological small vessel disease which usually affects respiratory tract and kidneys. However, salivary gland involvement in GPA primary manifestation. We report case of the presentation submandibular involvement. A 48-year-old female patient presented swelling skin defect that lasted for 1 month. Although biopsy result was chronic inflammation, did not heal Further imaging study revealed multiple lung renal masses. More clinical manifestations such gingivitis, ischemic change finger joint nasal tip skin, positive c-ANCA test presented. Additional made at gland, lung, skin. The finally diagnosed treated steroid pulse therapy cyclophosphamide. showed improvement prior symptoms.